Determination of ceftriaxone, ceftizoxime, paracetamol, and diclofenac sodium by capillary zone electrophoresis in pharmaceutical formulations and in human blood serum

نویسندگان

  • Amber SOLANGI
  • Saima MEMON
  • Arfana MALLAH
  • Najma MEMON
  • Muhammad Yar KHUHAWAR
  • Muhammad Iqbal BHANGER
چکیده

Amber SOLANGI1,∗, Saima MEMON, Arfana MALLAH, Najma MEMON, Muhammad Yar KHUHAWAR, Muhammad Iqbal BHANGER National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro-PAKISTAN e-mail: [email protected] Institute of Advance Research Studies in Chemical Sciences, University of Sindh, Jamshoro-PAKISTAN M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro-PAKISTAN

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Rapid Determination of Diclofenac in Pharmaceutical Formulations by Capillary Zone Electrophoresis

Capillary electrophoresis is competitive to HPLC and other chromatographic methods, predominantly when charged analytes have to be separated. The time of analysis can be reduced by the use of very short capillaries applying a high voltage. In most instruments which are commercially available the so-called 'short end' of the capillary can be used for separation, leading to very rapid separations...

متن کامل

Quantitative Analysis of Eight Cephalosporin Antibiotics in Pharmaceutical Products and Urine by Capillary Zone Electrophoresis

A simple and rapid capillary zone electrophoretic (CZE) method has been established for separation and quantification of a mixture of eight cephalosporins – cefadroxil (CFL), cefixime (CIX), cefuroxime sodium (CFR), ceftriaxone sodium (CTR), ceftizoxime (CFT), cefaclor (CFC), cefradine (CFD), and cefotoxime (CTA). Conditions affecting the separation were pH, buffer concentration, and applied po...

متن کامل

Determination of Aciclovir and its Related Substance Guanine in Bulk Drug and Tablet Preparation by Capillary Electrophoresis

Two Capillary Zone electrophoresis (CZE) methods were developed in this study, one using an acidic buffer (sodium citrate pH = 2.5) and the other using a basic buffer (sodium tetraborate pH = 9.8). The two methods were compared on the basis of repeatability and reproducibility of results and the CZE method developed with the basic buffer was then selected for further studies. The method was ful...

متن کامل

Evaluation of Acetonitrile Deproteinisation of the Serum Samples for the Analysis of Drugs in Serum Using Capillary Zone Electrophoresis

Deproteinisation with acetonitrile (along with methanol or other reagents) is a useful and rapid technique in analysis of drugs or their metabolites in human serum. In this paper application of this simple technique in biopharmaceutical analysis using capillary electrophoresis (CE) is evaluated. Some drugs with different ionic and protein binding properties were selected and dissolved in human ...

متن کامل

Determination of Aciclovir and its Related Substance Guanine in Bulk Drug and Tablet Preparation by Capillary Electrophoresis

Two Capillary Zone electrophoresis (CZE) methods were developed in this study, one using an acidic buffer (sodium citrate pH = 2.5) and the other using a basic buffer (sodium tetraborate pH = 9.8). The two methods were compared on the basis of repeatability and reproducibility of results and the CZE method developed with the basic buffer was then selected for further studies. The method was ful...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010